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#012 Dr. Ronald Krauss on LDL Cholesterol, Particle Size, Heart Disease & Atherogenic Dyslipidemia

Aug 27, 2015
Dr. Ronald Krauss discusses cholesterol, LDL vs HDL, dietary impact on heart health, misconceptions about cholesterol & CVD risk, statins, and refining risk assessment through cholesterol particle size measurement in an enlightening and informative episode.
01:23:39

Episode guests

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Quick takeaways

  • LDL particle size impacts heart disease risk, with small dense particles posing greater danger due to artery wall accumulation.
  • Dietary factors like saturated fats and carbohydrates influence lipoprotein metabolism and heart disease risk differently.

Deep dives

Understanding LDL and HDL Cholesterol

LDL and HDL cholesterol play critical roles in heart disease risk. LDL cholesterol encompasses different particle sizes ranging from small and dense to large and buoyant, with smaller particles associated with higher heart disease risk. Despite higher LDL cholesterol being linked to heart disease, the smaller dense particles pose more danger due to their tendency to accumulate in artery walls and cause damage. On the other hand, HDL cholesterol, known as 'good' cholesterol, plays a role in removing excess cholesterol from tissues, lowering heart disease risk. Atherogenic dyslipidemia, characterized by high small LDL, low HDL, and high triglycerides, is a crucial measure of heart disease risk.

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