FantasyPros - Fantasy Football Podcast

Best NFL Prop Bets For Week 16 (Ep. 1912)

Dec 20, 2025
Discover expert prop bets for Week 16 as the hosts dive into standout players. Amon-Ra St. Brown's over on receiving yards is highlighted alongside Ladd McConkey's promising matchup. Expect Nico Collins to shine against the Raiders and De'Von Achane to thrive in his safety-net role. Jacoby Brissett is predicted to surpass his passing yards with a struggling defense ahead. The duo also shares touchdown picks, featuring Mike Evans and Travis Kelce, making this a can't-miss guide for your betting needs!
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ADVICE

Lock Early On Strong Home WR Props

  • Bet Amon-Ra St. Brown over his receiving yards in Detroit due to strong home performance and target share.
  • Lock in early lines (e.g., 81.5) before the number rises to get better value.
ADVICE

Exploit Weak Secondaries With Low Totals

  • Take Ladd McConkey over 46.5 receiving yards versus the Cowboys secondary, which ranks poorly in PFF coverage.
  • Use projections (PFF, BettingPros) and matchup grades to justify low-yardage overs.
ADVICE

Pick The Primary Target In Shootout Spots

  • Play Nico Collins over 61.5 receiving yards since he's the Texans' primary target and has cleared this mark repeatedly.
  • Assume the Texans will need passing yards even if the game skews toward a blowout.
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