Insights from Uncommon Thinkers: How these innovators found novel approaches in their fields
Dec 14, 2024
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Ingrid Swanson Pultz, CTO at Mopac Biologics, discusses her groundbreaking development of a gluten-destroying enzyme that offers hope for celiac patients. Chris Dunckley from TerraPower Isotopes reveals how his team transforms radioactive waste into cancer therapies, focusing on innovative techniques like extracting thorium-229. Andy Lapsa, CEO of Stoke Space, shares insights on creating fully reusable space vehicles using liquid cooling technology. Together, they embody the spirit of 'uncommon thinking' in driving impactful change across their fields.
ZAP Energy's pursuit of fusion energy through smaller, simpler devices could revolutionize global power production and mitigate resource conflicts.
Mopac Biologics' gluten-destroying enzyme represents a significant medical advancement for celiac disease, improving patients' quality of life through innovative protein design.
Deep dives
The Promise of Fusion Energy
Fusion energy holds the potential to provide a limitless and carbon-free power source for the planet, offering a sustainable solution for global energy needs. This energy source could eliminate conflicts related to natural resource scarcity, as it would not depend on geographical locations or traditional energy resources. Researchers at ZAP Energy are pursuing a more cost-effective approach by utilizing smaller fusion devices which require simpler engineering than conventional large-scale systems. Although progress is anticipated to take about a decade before fusion energy becomes viable for consumption, the implications of successful fusion technology could revolutionize energy production and usage worldwide.
Advancements in Gluten-Destroying Enzymes
The development of gluten-destroying enzymes is a significant advancement in addressing celiac disease, aiming to improve the quality of life for individuals affected by this condition. Scientists at Mopac Biologics are applying protein design techniques to create enzymes capable of breaking down gluten in the harsh environment of the human stomach. Their innovative approach utilizes an enzyme derived from a bacterium found in Japan, which has been engineered to specifically target gluten. Early experiments conducted with local food chains demonstrate the enzyme's effectiveness, with potential for further clinical trials and eventual commercial applications.
Transforming Radioactive Waste into Cancer Treatment
The team at TerraPower Isotopes focuses on converting radioactive waste into vital resources for cancer therapy, specifically by extracting actinium-225 from thorium-229 isotopes. This innovative endeavor stems from recognizing the untapped potential in radioactive waste that could otherwise be disposed of inefficiently. Their successful extraction processes have enabled the constant supply of actinium to drug developers, supporting the advancement of targeted alpha therapies for various cancer types. With ongoing research and development, this initiative could significantly enhance treatment options for patients suffering from different forms of cancer in the coming years.
Innovating Reusable Space Vehicles
Stokespace is focused on developing a fully and rapidly reusable space vehicle, seen as essential for the long-term sustainability of the space economy. By addressing the costly and complex challenges of launching into orbit, the company aims to facilitate greater access to space, enabling innovations across numerous industries. Their unique design employs a liquid-cooled heat shield for more efficient reusability, differing from traditional materials like ceramic tiles used by other companies. This innovative method not only lowers costs but also increases the reliability and frequency of space missions, which are crucial for the next generation of space exploration and commercial endeavors.
This week on the GeekWire Podcast, we sit down with some of the Seattle region’s “Uncommon Thinkers” — inventors, scientists, technologists and entrepreneurs transforming industries and driving positive change in the world.
Uri Shumlak, co-founder and chief scientist at Zap Energy, a physicist leading a team in pursuit of fusion energy, taking a different approach from others in the field.Read the profile.
Andy Lapsa, aerospace engineer and CEO of Stoke Space, a company focused on developing fully and rapidly reusable space vehicles using a liquid cooling technique for re-entry. Read the profile.