Podnosis
Closing gaps in clinical trial infrastructure
Nov 13, 2024
In this insightful discussion, Alexander Saint-Amand, Co-founder and CEO of Topography Health, tackles the complex issues surrounding U.S. clinical trials, particularly for marginalized groups. He highlights the logistical and financial barriers limiting access and the decline in physician participation. Saint-Amand passionately advocates for enhancing trust and infrastructure within the sector, emphasizing the potential of AI to streamline patient recruitment. Additionally, he discusses strategies for engaging underserved communities in meaningful clinical research.
24:12
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Quick takeaways
- Access to clinical trials is limited for marginalized groups, with less than 5% of lung cancer patients participating in studies.
- Healthcare systems must view research as integral to patient care, requiring dedicated infrastructure to improve trial enrollment opportunities.
Deep dives
Challenges in Accessing Clinical Trials
Access to clinical trials in the U.S. is severely limited, especially for marginalized groups, with less than 5% of lung cancer patients able to participate in potentially life-saving studies. Many healthcare systems and community practices struggle financially to support research programs, often losing money or failing to recognize their losses. Specialized clinical research organizations (CROs) primarily cater to pharmaceutical companies, leaving healthcare providers without adequate support services. This disconnect results in a significant drop in doctor participation outside major academic centers, contributing to ongoing challenges in patient recruitment and access to clinical trials.
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