Tired, Sad, Unmotivated? This Hormone Might Be Why

Jul 10, 2025

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In this episode, Dr. Brandon and Dr. Morgentaler talk about how testosterone levels relate to age, weight, vitality, and long-term health—highlighting surprising research, the impact of obesity, and why staying lean may be the secret to aging well. 00:08 Testosterone and Aging: An Overview Dr. Morgentaler and Dr. Brandon open the episode with a candid look at how aging affects testosterone—and why it's more complex than most people think. 01:00 Symptoms and Diagnosis of Low Testosterone From low libido to lack of vitality, they explore subtle signs of low testosterone and the importance of testing even when symptoms aren't obvious. 03:42 Research Insights on Testosterone Levels They break down surprising research showing that average testosterone levels may not decline as much with age—but free testosterone tells a different story. 09:39 Impact of Weight and Lifestyle on Testosterone The doctors highlight how obesity is a major driver of low testosterone and explain how weight loss or GLP-1s can help restore healthy levels. 16:48 Concluding Thoughts and Final Tips The episode wraps with key takeaways: stay lean, stay engaged, and don't overlook testosterone—especially in overweight or aging men. Resources: Wu, F. C. W., Tajar, A., Beynon, J. M., Pye, S. R., Silman, A. J., Finn, J. D., ... & Forti, G. (2010). Identification of late-onset hypogonadism in middle-aged and elderly men. New England Journal of Medicine, 363(2), 123–135. https://doi.org/10.1056/NEJMoa0911101 Wu, F. C. W., Tajar, A., Pye, S. R., Silman, A. J., Finn, J. D., O'Neill, T. W., ... & EMAS Group. (2008). Hypothalamic-pituitary-testicular axis disruptions in older men are linked to age and modifiable risk factors: The European Male Ageing Study. The Journal of Clinical Endocrinology & Metabolism, 93(7), 2737–2745. https://doi.org/10.1210/jc.2007-1972 Huhtaniemi, I., Forti, G., & EMAS Study Group. (2012). Profile of the European Male Ageing Study (EMAS): Background, aims, and study design. Archives of Gerontology and Geriatrics, 54(3), e547–e556. https://doi.org/10.1016/j.archger.2011.11.014 With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon #MensHealth #TestosteroneLevels #HealthyAging