Optimal Protein Podcast with Vanessa Spina Light, Leptin & Fat Loss: How Circadian Biology Controls Metabolism — Dr. Catherine Clinton
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In this episode, I'm joined by Dr. Catherine Clinton to explore how circadian biology, light exposure, and cellular electrical charge regulate metabolism, hormones, and fat loss — often beyond calories alone.
We discuss how morning light impacts leptin signaling, insulin sensitivity, cortisol, and melatonin, why modern indoor living disrupts metabolic health, and how maintaining a strong negative cellular charge is critical for mitochondrial function.
We also cover red and infrared light therapy, optimal timing, metabolic benefits, and key considerations during pregnancy — plus how to integrate protein intake, calories in vs. calories out, and resistance training with circadian alignment for sustainable fat loss.
Topics include:-
Light exposure and leptin signaling
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Circadian rhythm and fat loss
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Cellular charge and mitochondrial health
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Grounding and infrared light
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Red light therapy timing and pregnancy considerations
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Balancing calories, protein, and training with circadian biology
🔗 Dr. Catherine Clinton's book Optimize: drcatherineclinton.com/optimize
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The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.