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Science, Spoken

Not Everyone Loses Weight on Ozempic

Jul 2, 2024
Exploring the variability in weight loss responses to GLP-1 drugs, researchers delve into genetic variations and physiological factors. Factors affecting weight loss and obesity phenotypes are discussed, including how machine learning categorizes individuals for enhanced benefits from GLP-1 drugs.
09:11

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Quick takeaways

  • Effectiveness of GLP-1 drugs varies due to genetics and metabolism.
  • Commitment to lifestyle changes and adherence to medication play key roles in weight loss outcomes.

Deep dives

Variability in Response to Anti-Obesity Drugs

Not all patients experience significant weight loss on GLP-1 drugs like Ozempic and Wigovi. Clinical trials show around 15-20% weight loss on average, but real-world results vary. Factors such as genetics, metabolism, and other medications can influence the effectiveness of these drugs. While some individuals benefit greatly, others may not respond well and could experience side effects that outweigh the minimal weight loss.

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