Eagle's Eye View: Your Weekly CV Update From ACC.org ORBITA-2 & PCI; Blood Pressure Control & Increasing Medication Prescriptions; Rapid Initiation & Titration in GRMT for Patients with HFrEF
May 14, 2025
Discover the intriguing results of the ORBITA-2 Trial and its implications for stress echocardiography before PCI. Delve into why some patients struggle to achieve blood pressure control despite escalating their medication. Finally, learn about the promising strategies for rapid initiation and titration of guideline-recommended therapies in those grappling with heart failure and reduced ejection fraction. Each topic sheds light on evolving practices and their impact on patient care.
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Stress Echo Predicts PCI Success
- Stress echocardiography (DSE) scores predict PCI benefits in angina patients with coronary disease.
- Higher ischemia indicated by DSE correlates with greater angina relief and quality of life improvement post-PCI.
Blood Pressure Control Plateaus
- Despite increased antihypertensive prescriptions, blood pressure control plateaued around 70%.
- Patient reluctance and clinical limitations hinder optimal hypertension management.
Barriers to Rapid HFrEF GDMT
- Rapid initiation and titration of guideline-directed medical therapy (GDMT) in HFrEF is feasible but often suboptimal.
- Clinic scheduling and system support are major barriers to timely dose optimization.