NFL Daily with Gregg Rosenthal

Week 16 NFL Picks with Cynthia Frelund

Dec 19, 2025
Cynthia Frelund, an NFL Network analytics expert known for her predictive modeling, joins to share her daring Week 16 picks. She confidently forecasts a Texans blowout against the Raiders, while Gregg Rosenthal warns about the Lions' injuries affecting their game against the Steelers. Cynthia highlights Tyler Shuck's potential breakout for the Saints and backs the Packers to cover against the Bears due to their defensive gaps. They also analyze the Chargers’ offense and the Bills' immense advantage over the struggling Browns.
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ANECDOTE

11-Week Pick Streak And A Saved Bet

  • Gregg celebrates an 11-week winning streak on their three-game weekly picks and notes last week's 3-0 result.
  • He credits Cynthia for talking him out of one risky pick that would have jeopardized the streak.
INSIGHT

Chargers' Grit Trumps Matchup Doubt

  • Gregg Rosenthal senses the Chargers possess a resilient culture that leads them to win tight, chaotic games.
  • He believes their physical play and Justin Herbert's leadership can overcome matchup doubts against the Cowboys.
ADVICE

Avoid Reactionary Model Swings

  • Cynthia Frelund notes modelers shouldn't flip probabilities wildly after single events and favors measured confidence ranges.
  • Use conservative probability shifts to avoid reactionary overcorrections in predictive models.
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