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N-M-N is a supplement that is touted as the new frontier in anti-aging, with claims of enhancing lifespan and reducing negative effects associated with aging. It is a derivative of vitamin B3 and has been shown to increase NAD+ levels in the body. Animal studies have indicated positive effects on cardiovascular health and insulin sensitivity. However, human studies have yielded mixed results, with some showing increased NAD+ levels but limited improvements in cardiometabolic health and physical performance. The evidence for cognitive improvement is also inconclusive. It is important to note that many N-M-N supplements on the market may not contain the stated amount of N-M-N or any at all.