ID:IOTS - Infectious Disease Insight Of Two Specialists
58. Mythbusting Cidal vs Static with Microbe Mail
Aug 29, 2023
Guests Jame and Callum discuss the definitions of bactericidal and bacteriostatic antibiotics, the complexities of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC), and comparisons of cidal vs static antibiotics in specific clinical scenarios. They challenge the belief that cidal antibiotics are always superior, emphasizing the importance of selecting the most appropriate antibiotic based on pathogens and patients.
41:36
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Quick takeaways
- Clinical distinction between bactericidal and bacteriostatic blurs in real-world scenarios despite clear lab definitions.
- Evidence challenges the belief that bactericidal antibiotics are inherently superior to bacteriostatic alternatives in clinical efficacy.
Deep dives
Distinction between Bactericidal and Bacteriostatic Antibiotics
In clinical situations, the distinction between bactericidal and bacteriostatic antibiotics becomes blurred despite clear-cut lab conditions. Recent revelations challenge the myth that bactericidal is superior to bacteriostatic, demonstrating that the preference for cyal over static is unsubstantiated.
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