William bird discusses how healthcare focused on communities and acitve lifestyles can lead to greater wellbeing. We are entering the fourth revolution of healthcare. The first revolution was Public Health with sanitation, cleaner air and better housing. The second is medical healthcare with the advancement of diagnostics and treatment with a focus on disease cure. The third is personalised health, through individual knowledge, technology, behaviour change and precision medicine. However, these revolutions have left three major problems unresolved; unsustainable healthcare, rising health inequalities and climate change driven by unsustainable living. So, we enter the fourth revolution in healthcare which builds on the previous three. This is based on communities rather than individuals, supporting a sustainable active lifestyle, eating local produce and using culture, art and contact with nature to create purpose and connections to each other, leading to greater resilience and wellbeing. It is a revolution when Smart Cities become central to the delivery of health and when advanced technology becomes almost invisible encouraging a lifestyle closer rather than further from nature. In this talk Dr Bird will explain how we are already delivering this future and how biological changes such as chronic inflammation, epigenetics, mitochondrial dysfunction and telomere shortening can provide the scientific link between wellbeing and disease.