Aug 09 2024 This Week in Cardiology

Aug 9, 2024

John Mandrola, MD, a leading cardiologist, dives into critical cardiology topics this week. He discusses the tug-of-war between clinical prediction models and personal judgment in patient care. The conversation also covers the intricacies of CCTA quantification of atherosclerosis and its implications for cardiovascular risk. Mandrola examines the combined approach of AF ablation with LAAO, along with the efficacy of atrial shunt devices, highlighting recent studies that question their overall benefits for heart failure patients.

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Exploring the Balance Between Prediction Models and Clinical Judgment in Cardiology

00:00 • 28min

Prediction models vs clinical judgement, CCTA quantification of atherosclerosis, AF ablation plus LAAO, atrial shunt devices, and HF medical therapy are topics John Mandrola, MD, covers this week.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I.Clinical Prediction Models vs Clinical Judgement

Did Statin Decision-Making Just Get Harder?

https://www.medscape.com/viewarticle/did-statin-decision-making-just-get-harder-2024a1000egl

Colunga-Lozano and colleagues
https://doi.org/10.1016/j.jclinepi.2023.10.016
Aug 02, 2024 This Week in Cardiology Podcast
https://www.medscape.com/viewarticle/1001429

II. CCTA Quantification of Atherosclerosis

Atherosclerosis Quantification and Cardiovascular Risk: the ISCHEMIA Trial https://doi.org/10.1093/eurheartj/ehae471
Circulation ISCHEMIA sub study 2021 – Severity of CAD and Outcomes https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.049755
ISCHEMIA Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1915922

III. Combined AF Ablation and LAAO

Review from Mills and colleagues https://doi.org/10.1016/j.tcm.2023.11.003
Link to CMS Rule on AF Ablation and LAAO https://hrs2.informz.net/z/cjUucD9taT05MjU3ODgyJnA9MSZ1PTkwMDQ2MTk4MCZsaT04NTU1OTQxMg/index.html

IV. Atrial Shunt Devices

No Net HF Benefit for Interatrial Shunt Device

https://www.medscape.com/viewarticle/no-net-hf-benefit-interarterial-shunt-device-2024a10006kk

Original REDUCE-LAP-HF-II https://doi.org/10.1016/S0140-6736(22)00016-2
Two-year results of REDUCE-LAP-HF-II https://doi.org/10.1016/j.jchf.2024.04.011
Apr 19, 2024 This Week in Cardiology Podcast

V. Optimal HF Therapy

Rao and colleagues; CHAMP HF https://doi.org/10.1016/j.jchf.2024.05.026

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