emDOCs.net Emergency Medicine (EM) Podcast Episode 113: Immune Checkpoint Inhibitor Adverse Events
11 snips
Jan 27, 2025 Dive into the world of immune checkpoint inhibitors in cancer therapy. This discussion reveals their fascinating impact on the immune system and the various adverse events they can trigger across organ systems. Learn about essential management strategies and the critical role of early intervention to prevent complications. It's a deep yet engaging examination of a cutting-edge topic in medicine that could change patient outcomes significantly!
AI Snips
Chapters
Transcript
Episode notes
Mechanism and Adverse Event Rates
- Immune checkpoint inhibitors unleash T-cells by blocking cancer's suppressive signals.
- They cover four main classes affecting up to 90% of patients with certain adverse events.
Check Meds and Consult Oncologist
- Always review medication history for immune checkpoint inhibitor use in cancer patients.
- Consult the oncologist early to manage adverse events properly.
Manage Immune Colitis Effectively
- For colitis, grade severity by stool frequency and symptoms.
- Use stool studies, imaging, and steroids for grade 2+ cases; involve surgery if severe.