On this episode of 49ers Talk, Matt Maiocco and Laura Britt discuss some recent news surrounding the 49ers, including facing former quarterback Alex Smith this weekend and changes to the team's schedule. Then, 49ers offensive lineman Trent Williams joins the show to discuss his time in Washington and what his future holds. Finally, 49ers analyst Takeo Spikes and NBC Sports Washington’s JP Finaly stop by to preview the Week 14 matchup between San Francisco and Washington.

(3:47) 49ers face Washington in Week 14 matchup

(10:36) Will Trent Williams re-sign with the 49ers?

(17:05) Williams discusses his battle with cancer

(22:50) Williams details playing for the 49ers

(30:10) Williams reveals his thoughts on his future

(35:22) Spikes reflects on being a teammates with Alex Smith

(44:10) Should Smith win Comeback Player of the Year?

(49:08) San Francisco, Washington trending in different directions

(54:03) Finlay discusses Smith’s leadership in Washington

271. Trent Williams on 49ers future, Alex Smith comeback stories