Dr. Daniel Griffin, an infectious disease clinician and researcher, offers a wealth of insights on viral infections. He discusses concerning links between in utero SARS-CoV-2 exposure and neurodevelopmental issues in children. The benefits of HPV vaccination in enhancing viral clearance are explored, alongside the troubling rise in measles cases among vaccinated healthcare workers. He also highlights the effectiveness of Paxlovid in reducing COVID-related hospitalizations and the role of vaccination in preventing long COVID in adolescents, making a strong case for science in healthcare.
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insights INSIGHT
In-Utero COVID Raises Early Neurodevelopment Risk
Maternal SARS-CoV-2 infection during pregnancy associates with higher neurodevelopmental diagnoses by age three.
Third-trimester exposure produced the largest effect and male offspring were most affected.
insights INSIGHT
HPV Vaccine Shows Therapeutic Benefits
HPV vaccination can enhance viral clearance and lower recurrence after conization, even when given after infection.
Studies show remission up to 72% in vaccinated women versus 46% in controls and 87% lower recurrence after conization.
insights INSIGHT
Asymptomatic H5N1 Occurs In Humans
Asymptomatic human H5N1 infections have been documented, lowering the true infection fatality rate compared with early reported case-fatality rates.
The review found 18 reported asymptomatic H5N1 infections with molecular or serologic confirmation.
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In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how two vaccinated physicians became infected with measles, effective of COVID-19 vaccine for children, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how a specific antibody type may associate with recovery from long COVID, if use of a probiotic is helpful to treat mild COVID-19, if vaccination helps prevent long in adolescents and contacting your federal government representative to stop the assault on science and biomedical research.
Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero (Obstetrics & Gynecology)
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature)
TWiV 1267: A cancer vaccine and an mpox treatment (microbeTV: TWiV1267)
Cancers Caused by HPV (CDC: Human papillomavirus (HPV))
Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of National Cancer Institute)
Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine (Viruses)
Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England (LANCET: Child & Adolescent Health)
This Week in Virology 
