The Intern At Work: Internal Medicine 67. The Fungus Among Us- Candidemia
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Aug 9, 2020 Dive into the world of candidemia, a serious bloodstream infection caused by a dangerous fungus. Discover the microbiology behind Candida auris and its resistance to treatment. Learn about diagnostic techniques and management strategies to combat this infection. The discussion emphasizes the importance of timely medical intervention in saving lives. This insightful exploration sheds light on a critical yet often overlooked aspect of internal medicine.
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Discovery Of Candida Auris
- A 70-year-old Japanese woman with otitis externa led to discovery of Candida auris from ear discharge.
- Whole genome sequencing revealed a multi-drug resistant Candida frequently misidentified in hospitals.
Shifting Candida Epidemiology
- Candida species are common human colonizers found on skin, mucosa, and the environment.
- Non-albicans and resistant species like C. glabrata and C. auris have risen due to healthcare changes.
Start With Stability And Source Hunt
- Assess stability first, then identify infection source and metastatic sites through focused history and exam.
- Ask about antibiotics, immune suppression, vascular access, surgeries, and perform head-to-toe exam for eyes, CNS, heart, joints, and abdomen.