

First10EM Journal Club :April 2025
Apr 17, 2025
Explore the intricate role of calcium in treating atrial fibrillation and the nuances of clinical decision-making in medicine. Discover the surprising connections between air pollution and venous thromboembolism while diving into airway management with a focus on capnography. The podcast also covers innovations in pediatric seizure treatment, addressing the challenges of rigid hospital protocols. With playful banter and engaging anecdotes, the hosts navigate through serious medical topics with humor and insight.
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Calcium Pre-treatment Is Unnecessary
- Pre-treating with calcium before diltiazem shows no clinical benefit in preventing blood pressure drop.
- Treatment focuses better on managing hypotension if it occurs rather than preemptive calcium use.
Beware Confounded Bleeding Risk Data
- Retrospective data showing more bleeding with diltiazem and DOACs is confounded by different patient profiles and co-medications.
- The study's control group mismatch invalidates conclusions about bleeding risk.
Decision Rules Often Increase Testing
- Clinical decision rules often do not outperform experienced clinical judgment.
- Many rules increase testing rather than reduce it due to prioritizing sensitivity over specificity.