83: The Gut-Autoimmune Connection: Breaking the Cycle of Leaky Gut & Chronic Illness | Dr. Vincent Pedre

In this episode of Thyroid Pharmacist Healing Conversations, Dr. Izabella Wentz interviews functional medicine physician Dr. Vincent Pedre about the hidden root causes of IBS, gut inflammation, and chronic digestive symptoms that often precede autoimmune disease.

Together, they explore how stress physiology, nervous system dysregulation, environmental toxins, mold exposure, microplastics, and mitochondrial dysfunction can damage the gut – even in people who are already gluten-free and eating “clean.” Dr. Pedre also debunks common myths about coffee and gut health, sharing how high-quality, clean coffee can be enjoyed without triggering reflux or inflammation.

What you’ll learn in this episode:

• Why IBS is often the first warning sign of deeper immune dysfunction. Dr. Pedre explains how years of gut inflammation can dysregulate the immune system, increase intestinal permeability, and eventually contribute to autoimmune conditions like Hashimoto’s – long before labs reveal antibodies.

• How stress and nervous system dysregulation quietly sabotage digestion – even when you feel “fine.” Chronic stress suppresses vagal tone, lowers stomach acid and enzyme production, and slows gut motility. Your body always tells the truth.

• The hidden gut disruptors most people never test for. Mold exposure, parasites, yeast overgrowth, microplastics, and environmental toxins can damage the gut lining and microbiome, even without classic digestive symptoms.

• Why elimination diets don’t always lead to true healing. Removing foods can reduce symptoms, but true healing often requires repairing the gut barrier, addressing toxin load, supporting mitochondria, and calming the nervous system.

• The truth about coffee, gut health, and thyroid symptoms. Coffee itself isn’t the enemy – poor-quality beans, mold contamination, pesticides, over-roasting, and plastic exposure are. Dr. Pedre shares information on coffee that is cleaner and gentler on the gut.

• How targeted therapies can dramatically speed gut healing. Dr. Pedre shares how phospholipids, peptides, sauna therapy, and mitochondrial testing are helping patients tolerate foods again – often in months instead of years.

Tune in to learn how to heal your gut at the root – and reclaim your health.

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For the full list of resources and products mentioned in this episode, and to get the full episode transcript, see complete show notes here: ⁠https://thyroidpharmacist.com/articles/podcast/

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