Globally, more than 200 million infants have been born since the onset of the COVID-19 pandemic. It has been unclear whether fetal exposure to maternal SARS-CoV2 infection can adversely affect the child’s neurodevelopmental progress. Does having Covid during pregnancy affect the child’s neurodevelopment? The answer is intriguing! This is a tale of a pandemic, psychosocial stress response, and epigenetic changes. (Data summary from JAMA Pediatrics; Jan 2022).