The World as You’ll Know It: The Future Of Aging The Truth About Biohacking
May 27, 2025
In this engaging discussion, Nobel Prize-winning biochemist Venki Ramakrishnan and epidemiologist Daniel Belsky delve into the world of biohacking. They explore the science and hype behind methods like caloric restriction, rapamycin, and metformin for extending lifespan. Belsky shares insights on his innovative blood test that reveals biological aging, offering a new perspective on how quickly our bodies age. Together, they shed light on the balance between scientific research and the booming biohacking industry, urging caution amidst the excitement.
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Extreme Biohacking Journey
- Brian Johnson uses extreme biohacking methods, including blood transfusions from his teenage son, to fight aging.
- He invests millions annually and promotes this lifestyle to a large following, calling it a movement or religion.
Caloric Restriction Clears Cellular Junk
- Caloric restriction triggers cellular "garbage disposal" by activating autophagy to clear defective components.
- This cleanup helps maintain youthful cellular function but cannot fully prevent aging.
Rapamycin’s Anti-Aging Potential
- Rapamycin suppresses the cell growth switch, mimicking effects of caloric restriction and extending life in mice.
- It shows promise as an anti-aging drug but requires cautious dosage to balance immune suppression risks.
