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Continuum Audio

Vascular Cognitive Impairment With Dr. Lisa C. Silbert

Dec 18, 2024
Dr. Lisa C. Silbert, a behavioral neurologist at Oregon Health & Science University, delves into vascular cognitive impairment—often overlooked yet crucial in aging. She discusses how cerebrovascular diseases can modify dementia risk, emphasizing the need for accurate diagnosis through detailed histories and MRI scans. The conversation also highlights enlarged perivascular spaces' role in neurodegenerative conditions and the significance of cerebral amyloid angiopathy. Dr. Silbert calls for more research, especially focusing on blood-based biomarkers to enhance cognitive health.
20:28

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Quick takeaways

  • Vascular cognitive impairment is often gradual, highlighting the necessity for clinicians to broaden diagnostic criteria beyond acute stroke events.
  • Preventing vascular disease through lifestyle changes is crucial for cognitive health, as socioeconomic disparities affect access to these interventions.

Deep dives

Understanding Vascular Cognitive Impairment

Vascular cognitive impairment has evolved into a key area of focus within neurology, moving beyond acute declines associated solely with stroke events. It's essential to recognize that various forms of vascular cognitive impairment can result in more gradual and progressive cognitive declines, expanding the diagnostic criteria for clinicians. Such impairments often coexist with other types of dementia, and cerebrovascular disease can lower the threshold for cognitive impairments when multiple pathologies are present. This broadens the scope for treatment and emphasizes the need for clinicians to consider vascular contributions as both significant and potentially modifiable aspects of dementia.

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