Developing a Life-Extending Medication for Large Breed Dogs

A San Francisco-based biotech firm called Cellular Long Jevity, through its dog arm Loyal, has partnered with pharma company Crinetics to develop a medication that aims to help large breed dogs live longer. The medication is currently undergoing the FDA approval process and has shown promising initial data. It focuses on reducing the levels of IGF-1 hormone, which is associated with shorter lifespans in large dogs. The drug is administered through injections every three to six months, and a larger efficacy study with a thousand dogs is planned. The aim is to extend the healthy lifespan of these dogs, but potential side effects and long-term effects are still being studied.