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The Curbsiders Internal Medicine Podcast

#466 Cirrhosis Update with Scott Matherly

Jan 13, 2025
Scott Matherly, an Associate Professor of Hepatology and Gastroenterology at Virginia Commonwealth University, dives into the complexities of cirrhosis management. He emphasizes the importance of thorough evaluations and timely referrals for liver transplants, discussing critical assessments like the MELD 3.0 scoring system. Listeners learn about managing decompensated cirrhosis, complications like ascites, and lifestyle changes to improve liver health. Personal anecdotes add depth, highlighting growth through challenges in both medicine and life.
01:21:58

Episode guests

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Quick takeaways

  • The initial evaluation of cirrhosis emphasizes lab work and imaging to identify complications like portal hypertension and guide treatment.
  • Timely referral for liver transplantation in patients with decompensated cirrhosis is crucial due to increased mortality risks and complications.

Deep dives

Understanding Liver Health and Cirrhosis

Cirrhosis is a chronic liver disease that results in the progressive deterioration of liver function, often requiring careful monitoring and management. The initial evaluation of cirrhosis includes sending specific lab work to identify possible causes, such as hepatitis viruses and metabolic disorders. Imaging studies play a critical role in assessing liver architecture, and any signs of nodularity or splenomegaly can suggest complications like portal hypertension. Recognizing these factors is imperative to determine the appropriate treatment protocols, including possible referrals for transplantation.

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