The Skeptics' Guide to the Universe cover image

The Skeptics' Guide to the Universe

The Skeptics Guide #1025 - Mar 1 2025

Mar 1, 2025
In this engaging conversation, Adam Russell, bassist for Story of the Year and co-host of Thank the Maker, reflects on the band's journey and resurgence, sharing how they've captured the hearts of a new generation. The discussion dives into innovative urban solutions like congestion pricing and the challenges posed by AI in mental health care. Adam also touches on the fascinating science behind dyslexia and small modular reactors for cargo ships, intertwining music, science, and community. Plus, he shares some light-hearted moments, including a guessing game about mysterious sounds!
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Quick takeaways

  • Utilizing mRNA technology to produce a unique protein from tardigrades shows promise in reducing radiation damage during cancer treatments.
  • Research indicates that many mammals exhibit unexpected activity patterns, prompting a reevaluation of classifications for ecological and conservation efforts.

Deep dives

Tardigrade Protein and mRNA Technology

Researchers have successfully utilized mRNA technology to produce a protein derived from tardigrades, aiming to protect surrounding tissue from radiation damage during cancer treatment. Tardigrades, known for their incredible resilience to extreme conditions, have a unique protein that binds to DNA and prevents its injury when exposed to radiation. In a recent study, mice were injected with mRNA that encoded this protein before being subjected to radiation therapy. This innovative approach showcased a significant reduction in DNA damage, providing hope for advancing cancer treatment modalities and minimizing collateral harm to healthy tissues.

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