Exploring the potential of a new class of drug candidates
Mar 12, 2024
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Exploring the potential of a new class of drug candidates with Vicore Pharma's CEO, focusing on angiotensin II type 2 receptor agonists for treating rare respiratory diseases. Discussions on technology, collaboration, challenges in addressing idiopathic pulmonary fibrosis, and opportunities in drug development in Sweden.
Vycor Pharma focuses on developing drugs that activate the AT2 receptor in the angiotensin II pathway to target rare respiratory diseases like idiopathic pulmonary fibrosis.
Compared to many cancers, idiopathic pulmonary fibrosis patients have a grim prognosis, emphasizing the urgent need for new treatment options like those developed by Vycor Pharma.
Deep dives
Vycor Pharma's Approach and Pipeline Focus
Vycor Pharma focuses on developing drugs that activate the AT2 receptor in the angiotensin II pathway. Initially targeting rare respiratory diseases like idiopathic pulmonary fibrosis, Vycor aims to harness a natural tissue repair system. They have generated promising clinical data in this area and are exploring digital therapies to support patients with pulmonary fibrosis.
Vycor Pharma's emphasis on idiopathic pulmonary fibrosis stems from the high unmet need in this area. Compared to many cancers, IPF patients face a grim prognosis of 3-5 years survival post-diagnosis. Existing therapies have challenging tolerability issues leading to low patient adherence, highlighting the urgency for new treatment options like those Vycor Pharma is developing.
Technological Uniqueness and Collaborative Approach
Vycor's uniqueness lies in its adeptness at modulating the angiotensin-2 type-2 receptor, a challenging target expressing on lung cells. Through strong collaborations with academic and clinical communities, Vycor gains insights, validates approaches, and refines its therapies. Their technology foundation in the 82 receptor space is critical to their innovative drug development efforts.
In the In Conversation Withseries, a part of the free DDW podcast, DDW speaks with members of the drug discovery industry about their work and how it helps turn science into business.
In this episode, Megan Thomas is in conversation with Ahmed Mousa, CEO of Vicore Pharma. Vicore Pharma is exploring the potential of a new class of drug candidates, angiotensin II type 2 receptor agonists (ATRAGs), and here Mousa provides DDW with an overview of the company’s unique approach, its challenges, its opportunities, and its context in the scientific community.