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Highlights: #202 – Venki Ramakrishnan on the cutting edge of anti-ageing science
Oct 4, 2024
Venki Ramakrishnan, a Nobel Prize-winning molecular biologist and author of 'Why We Die', takes a deep dive into anti-aging science. He challenges the idea of death as an unavoidable aspect of evolution, suggesting that future research could significantly extend healthspan. The discussion touches on the potential social implications of life extension, including rising inequality. Ramakrishnan also examines controversial practices like young blood transfusions and the ethical dilemmas surrounding these radical methods.
23:10
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Quick takeaways
- Aging research focuses on enhancing healthspan through advancements like targeting nutrient sensing pathways and eliminating senescent cells.
- Increased longevity poses societal challenges, necessitating adjustments to workforce dynamics and addressing potential inequality among different age groups.
Deep dives
Evolution and Aging
Death is viewed as a result of evolutionary processes, with no inherent programming for mortality. Organisms are optimized for reproductive fitness rather than longevity, leading to different life spans across species. For example, smaller animals like mice typically have shorter lives due to higher predation risks, while larger animals benefit from a longer lifespan, enhancing their reproductive opportunities. The relationship between size and longevity illustrates the varying evolutionary pressures that shape different species' lifespans.
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