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Early Prospective Tracking Revealed Long Covid
- Prof. Jack Lambert tracked ~1,700 COVID patients prospectively from March 2020 onward.
- Early follow-up revealed many patients develop persistent post-infectious symptoms similar to other coronaviruses.
Brain Damage Explains Many Persistent Symptoms
- COVID often damages the brain's posterior regions causing persistent symptoms while heart and lungs usually heal.
- Affected areas control balance, pain, respiration and autonomic nervous function.
Mitochondrial Dysfunction Causes Crashes
- Patients often 'crash' after exertion due to mitochondrial dysfunction or a mitochondrial-like crash.
- That explains post-exertional malaise and inability to sustain activity without severe fatigue.