VJHemOnc Podcast cover image

VJHemOnc Podcast

Understanding BPDCN: dermatology and hematology perspectives on presentation, diagnosis, treatment, & multidisciplinary care

Nov 28, 2024
Expert guests Marlise Luskin, a hematology specialist, Nicole LeBoeuf, a dermatologist, and hematologist Shai Shimony from Dana-Farber Cancer Institute discuss blastic plasmacytoid dendritic cell neoplasm (BPDCN). They delve into its unique symptoms, including deep purple skin lesions, diagnostic challenges, and the necessity of a multidisciplinary approach. The conversation also highlights treatment options like tagraxofusp and venetoclax, advancements in targeted therapies, and the critical role of collaboration among healthcare professionals to improve outcomes for patients.
34:43

Podcast summary created with Snipd AI

Quick takeaways

  • Early recognition of distinct skin lesions is crucial for timely diagnosis of BPDCN, as symptoms can precede diagnosis by months.
  • Collaboration among hematologists and dermatologists enhances the accuracy of diagnosis and treatment of BPDCN, improving patient outcomes.

Deep dives

Understanding BPDCN: Clinical Presentation and Symptoms

Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare leukemia that exhibits characteristics similar to both leukemias and lymphomas. This malignancy often presents with unique skin lesions, which can vary in appearance from deep purple nodules to skin-colored bumps. Dermatologists may routinely encounter patients exhibiting multiple plum-colored patches, often attributing these initial symptoms to less severe conditions like bruises or bug bites. Recognizing these distinct markers is critical for timely diagnosis, as initial symptoms can significantly precede a formal identification by several months.

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode