ICU Primary PrepCast #033: Haematology Physiology
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Jul 1, 2020 Delve into the intricate dance of hemostasis, uncovering how your body stops bleeding after injury. Explore the dual processes of hemostasis and fibrinolysis, highlighting the roles of various proteins. Learn about the body's defenses against thrombosis, guided by Virkar's triad. Get insights on coagulation pathways vital for ICU care, and the crucial tests like ACT and Rotem that ensure patient safety. Conclude with a touch of humor, blending hematology jokes with financial success!
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Hemostasis Components
- Hemostasis involves vasoconstriction, platelet plug formation, and coagulation.
- These steps minimize blood loss after vessel injury.
Coagulation Pathways
- Coagulation involves intrinsic and extrinsic pathways converging into a common pathway.
- This leads to fibrin clot formation.
Fibrinolytic Pathway
- The fibrinolytic pathway degrades fibrin clots, counterbalancing coagulation.
- It involves plasminogen activators, plasmin formation, and clot lysis.