Translating Aging XPRIZE Healthspan: Catalyzing Therapies for Aging (Jamie Justice, PhD)
Dr. Jamie Justice is Executive Director of the newly launched XPRIZE Healthspan, a $101 M international competition to accelerate therapeutics targeting aging biology. In conversation with host Chris Patil, Dr. Justice outlines the motivation, structure, and timeline of the prize, as well as how teams can get involved. She also explains unique aspects of this prize, including the public commentary period, how existing trials can be adapted for competition, functional endpoints, and judging criteria. She also conveys why coordination is needed to overcome barriers and drive investment in longevity R&D. Listeners will gain key insights into this ambitious initiative to catalyze progress translating research into treatments for aging.
Key ideas:
- Why aging solutions need acceleration despite increased attention
- The role and track record of incentive competitions like XPRIZE
- Motivation and sponsors enabling XPRIZE Healthspan ($101M purse)
- Timeline from conceptualization to upcoming 7-year active competition
- Expert endpoint committee setting measurable functional criteria
- Initial public commentary period for radical collaboration with teams
- Phases: Intent to compete, qualifying submissions, finalist selection
- Existing prevention trials can add program assessments
- Common data and protocols to validate findings across teams
- Goal of demonstrating restoration of function across domains
- Secondary judging criteria around accessibility, biomarkers
- Driving global coordination, investment, and innovation
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