BMJ Best Practice Podcast

Alcohol-associated liver disease

21 snips
Dec 4, 2023
Professor Craig McClain, expert in alcohol-associated liver disease, discusses the diagnosis, management, and complications of this condition. He emphasizes the importance of obtaining a thorough drinking history and using biochemistry tests for diagnosis. Coagulation tests are explored in relation to monitoring the disease. The podcast also addresses common misconceptions and questions about alcohol-associated liver disease, including the harmful effects of underestimating alcohol consumption and the relationship between alcohol and opioids.
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INSIGHT

Disease Exists As A Spectrum

  • Alcohol-associated liver disease is a spectrum from fatty liver to steatohepatitis, cirrhosis, and cancer.
  • Early detection can prevent progression along this spectrum.
ADVICE

Take A Precise Drinking History

  • Take a clear drinking history and define a standard drink when assessing patients.
  • Use basic biochemical tests (AST, ALT, bilirubin) to support the diagnosis.
ANECDOTE

Veterans Are Often Frank About Drinking

  • Veterans often give frank drinking histories, unlike some other groups.
  • Craig McClain notes housewives may underreport due to social stigma.
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