The Dose How does nicotine affect cognition and what's the risk?
Feb 27, 2025
Steven Laviolette, a neuroscientist at the University of Western Ontario, dives into the complex effects of nicotine on cognition. He reveals how some non-smokers use nicotine to enhance attention and fine motor skills, despite its addictive potential. The conversation highlights how nicotine interacts with brain mechanisms to improve memory while discussing the risks of dependency, especially among younger users. Laviolette also warns of the double-edged nature of nicotine products, emphasizing the importance of seeking healthier alternatives.
AI Snips
Chapters
Transcript
Episode notes
Nicotine's Impact on Cognition
- Nicotine's cognitive enhancement stems from its interaction with nicotinic receptors in the brain.
- These receptors, found in areas like the frontal cortex and hippocampus, are linked to cognition and memory.
Smokers' Perceived Cognitive Edge
- Smokers often perceive a cognitive edge due to nicotine, but this can be confounded by withdrawal effects.
- Nicotine can improve cognitive function by alleviating withdrawal symptoms, but studies show it enhances cognition independently.
Nicotine and ADHD
- Nicotine's impact on dopamine and glutamate systems might explain its potential benefits for ADHD.
- It could normalize dopamine levels and regulate glutamate transmission in the frontal cortex, improving mental clarity.