The Resus Room January 2026; papers of the month
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Jan 1, 2026 This month's discussion dives into a cohort study revealing a chilling link between post-intubation hypotension and increased mortality in severe traumatic brain injuries. They also tackle whether elevated troponin levels in patients with stable supraventricular tachycardia are a reliable predictor of short-term cardiovascular events. Lastly, the hosts analyze the findings from a major trial on sodium bicarbonate for severe metabolic acidosis in acute kidney injury patients, emphasizing that it doesn't improve mortality but does reduce the need for renal replacement therapy.
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Podcast Hits 10 Years And Millions Of Downloads
- The Resus Room has reached 10 years and ~270 episodes, with over 7 million downloads, reflecting long‑term listener engagement.
- Hosts thanked listeners and Zoll Medical Corporation for supporting the podcast's free open‑access model.
Early Post‑Intubation Hypotension Raises Mortality
- Post-intubation hypotension within 10 minutes occurred in ~19% of prehospital RSIs for severe TBI and was linked to higher 30-day mortality.
- Adjusted odds of death were 1.7 overall and markedly higher (≈13.5) for isolated TBI, suggesting large harm from early BP drops.
BP Risk May Be Continuous, Not Binary
- The risk relationship appears continuous and may matter above the traditional 90 mmHg cutoff, with harm starting toward 100 mmHg.
- Observational data can reflect severity at baseline, so hypotension might partly mark catastrophic physiology rather than solely cause death.