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Neurology Exam Prep Podcast
Episode 59 - Myasthenia Gravis
Aug 5, 2023
A discussion on myasthenia gravis pathophysiology and diagnostic testing, including antibody disruptions at the neuromuscular junction. Treatment approaches for myasthenic crisis, respiratory monitoring, and long-term management with newer medications. Bedside examination maneuvers for respiratory and bulbar function assessment emphasized.
31:51
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Quick takeaways
- Myasthenia gravis presents with symptoms like diplopia, ptosis, and limb weakness, affecting different demographics.
- Pathophysiology involves disruption at the neuromuscular junction by antibodies, impacting neuromuscular transmission and function.
Deep dives
Clinical Presentation of Myasthenia Gravis
Myasthenia gravis often manifests with fatigueability, specifically in ocular and bulbar symptoms. Patients typically present with diplopia, ptosis, and fatigueable limb weakness. Symptoms can also include difficulty swallowing, speech problems, and fatigue with chewing. Myasthenia gravis can affect individuals of various demographics, with either younger women or older men being commonly affected.
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