
Stuff You Should Know The SAD Episode
22 snips
Jan 8, 2026 Delve into the serious side of seasonal affective disorder, or SAD, as the hosts differentiate it from mere winter blues. They explore onset timing, variants, and surprising gender differences. Discover the biological basis behind SAD, including how serotonin and melatonin play key roles. Treatment options range from medication to cognitive behavioral therapy. Insights on bright light therapy and cultural attitudes reveal resilience in combating this condition. A fascinating mix of science and real-world solutions awaits!
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SAD Is A Seasonal Major Depression
- Seasonal affective disorder (SAD) is a recognized subtype of major depressive disorder with a seasonal pattern.
- It most often begins in young adulthood, is more common in women, and usually appears in winter but can rarely occur in summer.
Suicide Peaks In Spring/Summer, Not Holidays
- Contrary to myth, suicides do not spike during December and are more common in spring and summer.
- Proposed explanations include greater energy to act and seasonal flares of autoimmune illnesses in warmer months.
Light Alters Serotonin And Melatonin
- Reduced sunlight lowers serotonin production and increases melatonin, disrupting mood and energy.
- In people with SAD the serotonin transporter doesn't downregulate in winter, so relatively less serotonin causes depressive symptoms.


