Dr Jason Fung on the impact of diet on obesity and type 2 diabetes mellitus

Dr. Jason Fung is a Consultant Nephrologist who trained and began his medical career at the University of Toronto before heading to the University of California in Los Angeles where he completed his fellowship in nephrology. Since then he has founded the Intensive Dietary Management Program, which provides a unique treatment for Type 2 Diabetes & Obesity. This BJSM podcast sees @Liam_West pose the questions and Dr. Fung take the listeners through the evidence behind the impact of diet on obesity and Type 2 Diabetes Mellitus (T2DM). Jason explains that, whilst the #LCHF model of “Carbohydrates  Insulin  Obesity” is not wrong, it is incomplete. He reiterates that the main player in the development of obesity and T2DM is INSULIN – not merely high carbohydrates. Jason believes that the calories in/calories out model that has previously been described is incorrect. He explains the evidence and builds upon the #LCHF model to include the importance of insulin resistance and meal timing. In T2DM, this resistance leads to Beta-cell dysfunction. Evidence exists that this process can be reversed and therefore T2DM should not be considered to be a chronic progressive disease – it is curable with bariatric surgery and caloric prescription. The take home message for the podcast from Jason is to eat #RealFood, #ConsiderInsulin and #EmpowerPatients to regain control over diabetes. Literature Discussed in Podcast & Further Reading INTERMAP Study (2003) - http://www.nature.com/jhh/journal/v17/n9/abs/1001605a.html KITAVA Study (1995)- http://www.sciencedirect.com/science/article/pii/S0026049599902585 Insulin Resistance - One - http://link.springer.com/article/10.1007/BF00279918 Insulin Resistance - Two - http://www.sciencedirect.com/science/article/pii/S0025712507000983 Insulin Resistance - Three - http://diabetes.diabetesjournals.org/content/56/4/984.short Lancet Infant Obesity (2010) - http://www.sciencedirect.com/science/article/pii/S0140673610601717 NEWCASTLE Study (2009) - http://www.biomedcentral.com/1471-2458/9/342/ Dietary Fibre reduces Insulin Resistance - http://jama.jamanetwork.com/article.aspx%3FarticleID=192034 Curing Diabetes – Surgical treatment diabetes - http://ajcn.nutrition.org/content/55/2/582S.short Curing Diabetes - Gastric Banding - http://jama.jamanetwork.com/article.aspx%3Farticleid=1149302 Curing Diabetes - Fasting & Bariatric Surgery - http://care.diabetesjournals.org/content/36/9/2741.short Curing Diabetes - ACCORD - http://www.nejm.org/doi/full/10.1056/NEJMe0804182 Curing Diabetes - Losing weight doesn’t work - http://www.nejm.org/doi/full/10.1056/NEJMoa033179 Curing Diabetes - Calorie restriction induces restoration of hepatic insulin sensitivity - http://care.diabetesjournals.org/content/36/4/1047.short Intensive Dietary Management Website - With educational lectures and other content - http://intensivedietarymanagement.com