TWiV 821: Public clonotype #1

A TWiV trio reveal the isolation of novel paramyxoviruses from rodents and bats in Arizona, and isolation of naive B cells from seronegative donors that produce germline encoded antibodies which engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses from bats.

Hosts: Vincent Racaniello, Rich Condit, and Brianne Barker

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Links for this episode

• Bat and rodent paramyxoviruses from Arizona (J Viral)
• Naive B cells engage SARS-CoV-2 RBD (Science Immunol)
• Vincent interviews Philip Sharp (ASM)
• Letters read on TWiV 821
• Timestamps by Jolene. Thanks!

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Brianne – Apod: The Dolphin Head Nebula Rich – The Tree That Could Help Stop The Pandemic; Elucidating the Mechanisms of Action of Saponin-Derived Adjuvants Vincent – Discovery of RNA splicing in Sharp and Roberts laboratories

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Jason – Home Assistant Alena – VirusCraft

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv