Run the List CKD: General Management
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Apr 28, 2025 Dr. Ryan Bonner, a nephrologist at UNC School of Medicine, shares his expertise on chronic kidney disease (CKD) management. He discusses innovative AI tools enhancing clinical efficiency and the importance of accurately assessing kidney function, including the role of cystatin C. The conversation navigates the complexities of medication management, highlighting challenges like polypharmacy and hyperkalemia. Dr. Bonner emphasizes a multidisciplinary approach to care, showcasing the critical need for teamwork among healthcare providers to optimize patient outcomes.
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Accurate Kidney Function Assessment
- Serum creatinine is the standard marker for estimating kidney function using the CKD-EPI equation.
- Cystatin C helps refine kidney function estimates in patients with abnormal muscle mass or certain medications.
Assessing CKD Progression Risk
- Risk assessment for CKD progression goes beyond a single eGFR value.
- The kidney failure risk equation (KFRE) incorporates eGFR and albuminuria to guide management and referral.
Maximize CKD Medication Use
- Keep CKD patients on evidence-based meds like ACE inhibitors, ARBs, SGLT2 inhibitors, and MRAs.
- Collaborate with pharmacists to manage side effects, polypharmacy, and financial barriers.