emDOCs.net Emergency Medicine (EM) Podcast
Episode 81: Hemophilia
Jul 11, 2023
Dr. Brit Long, an expert in hemophilia, discusses background, severity, evaluation, and management. Topics include different types of hemophilia, complications in patients, challenges in diagnosis, managing hemophilia in the emergency department, factor replacement therapy, risks for patients, and the importance of consulting hematology specialists.
16:07
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Quick takeaways
- Hemophilia is a bleeding disorder linked to deficient proteins in the coagulation pathway, leading to excessive bleeding.
- Management of hemophilia in the emergency department involves prompt assessment, resuscitation of life-threatening bleeds, and careful consideration of clotting factor replacement.
Deep dives
Understanding Hemophilia as a Bleeding Disorder
Hemophilia is a bleeding disorder with two main types: hemophilia A and hemophilia B. This condition results from a deficiency in the proteins of the coagulation pathway, leading to inadequate fibrin clot formation and excessive bleeding. Hemophilia can be inherited or acquired, affecting about 1 in 10,000 births. The severity of hemophilia is classified based on the levels of active factors present in the blood, ranging from severe (less than 1% factor availability) to mild (5-40% factor availability).
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