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What ‘Immortal’ Jellyfish and Famously Old Tortoises Tell Us about Aging

Jun 11, 2025
João Pedro de Magalhães, Chair of molecular biogerontology at the University of Birmingham, dives into the fascinating world of aging in animals. He explains how species like 'immortal' jellyfish and long-lived tortoises challenge our understanding of lifespan. The discussion touches on genetics and the role of DNA damage in aging, offering insights into potential longevity treatments for humans. Additionally, evolutionary history's impact on lifespan reveals why some creatures age gracefully while others do not.
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INSIGHT

Extreme Animal Lifespans

  • Animal lifespans vary greatly, from hours to centuries among different species.
  • Lifespan differences exist even among closely related mammals, like hamsters versus whales.
INSIGHT

Jellyfish's Biological Reversal

  • Some jellyfish can biologically reverse their development stages and effectively reset their aging process.
  • Aging and death can vary widely in phenotype depending on species' mechanical and biological constraints.
INSIGHT

Understanding Aging

  • Aging is a progressive physiological degeneration increasing vulnerability and decreasing viability.
  • Mortality risk doubles roughly every eight years after about age 30, a pattern seen across animals.
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