In what area should you work on, especially if you come from a developing country? In this presentation, Renan explains how many people's backgrounds position them uniquely to tackle certain problems from an angle that might not be the best for everyone else – especially those from LMIC. He goes through the importance, tractability, neglectedness framework and the concept of comparative advantage, and then explains how you can use these to find low-hanging fruits in fields like pandemic preparedness, international policy, and talent search.