Challenges in Ulcerative Colitis Treatment

Treating ulcerative colitis remains a challenge despite the availability of various medications. Patients with moderate to severe disease face hospitalizations and potentially colectomy. The primary goals of treatment are to induce remission and then maintain it to prevent reactivation of inflammation. For mild disease, 5-aminosalicylates are commonly used, while more advanced therapies target the pathogenesis of ulcerative colitis for moderate to severe cases.