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The Resus Room
January 2023; papers of the month
Jan 1, 2023
In this podcast, they discuss the benefits of thrombolytics or anticoagulants for patients in cardiac arrest due to a presumed MI, the potential harm of administering steroids to COVID-19 patients not requiring supplemental oxygen, and the use of point of care lactate in predicting the need for in-hospital blood product resuscitation.
29:26
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Quick takeaways
- Anticoagulation or thrombolytic therapy does not significantly improve outcomes in cardiac arrest patients without ST elevation or undergoing PCI.
- Steroids should not be used in non-oxygen requiring COVID-19 patients and should be reserved for those with more severe disease.
Deep dives
Thrombolysis and cardiac arrest: A systematic review and meta-analysis
A systematic review and meta-analysis examined the use of anticoagulation or thrombolytic therapy in cardiac arrest patients without ST elevation or receiving percutaneous coronary intervention (PCI). After analyzing three studies, the researchers found that the use of anticoagulation or thrombolytic therapy did not significantly improve risk attainment or hospital mortality. However, it was associated with higher rates of major bleeding. The study concluded that current evidence does not support the routine use of these treatments in cardiac arrest patients without ST elevation or undergoing PCI.
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