Understanding Pain Variability in Osteoarthritis

The experience of pain in osteoarthritis varies greatly among individuals. Some may feel intermittent pain tied to specific activities, while others endure constant, especially nighttime, pain. Pain descriptors like character, distribution, location, severity, and frequency differ widely. Experts suggest a biopsychosocial framework to comprehend pain origins, driven by factors like inflammation, loading, and nerve damage. Various pain types, including nociceptive, inflammatory, and neuropathic, are discussed, showcasing the intricate interplay causing joint pain.