Jen Psaki addresses the horrific shooting at a Catholic school in Minneapolis and the shocking gun statistics in the United States that "should make everyone angry." Psaki points to new gun legislation that passed under the Biden administration after a mass shooting at a supermarket, and reminds viewers that anger can turn into activism, activism can turn into pressure, and pressure can change laws.

Minneapolis Mayor Jacob Frey talks with Jen Psaki about the horrific shooting at Annunciation Catholic School that has left his community in shock and grief. Frey calls for Americans to recognize the victims of today's shooting not as somebody else's kids, "think about them as your own," and encourages a loving perspective but also real action to address America's gun problem.

The Trump administration is attempting to remove CDC Director Susan Monarez from her position after only two weeks in the Trump-appointed, Republican Senate-confirmed job. The conflict over Monarez's resistance to Trump HHS Secretary Robert F. Kennedy Jr.'s anti-science whims and conspiracy theories has apparently set of a series of other high-profile departures, leaving a vacuum at the top of the CDC and the Trump administration looking foolish.

Psaki: Action on America's gun problem is not hopeless