This Week in Cardiology Sep 26 2025 This Week in Cardiology
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Sep 26, 2025 Discover a groundbreaking trial in valvular heart disease that compares anesthesia methods for TAVI. Learn about the challenges to traditional views on VTE treatment and the unexpected results of a flu vaccination study. Explore promising data on oral GLP-1 agonists for weight loss and new insights into anticoagulation duration after provoked VTE. Tune in for essential updates on pulse-field ablation and helpful apps for heart care.
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Minimalist TAVI Can Be Noninferior
- A randomized trial showed a minimalist, no-sedation TAVI approach was noninferior to standard conscious sedation for 30-day composite outcomes.
- Careful patient selection, monitoring, and anesthesiology collaboration are essential because 21% crossed over due to pain.
Cultural Differences In Sedation Practice
- John finds it remarkable that German patients accept TAVI under local anesthesia without sedation while U.S. practice uses sedation widely.
- He contrasts cultural differences and personal experience offering sedation for minor procedures in the U.S.
Nudges Fail Without Trust
- The Kaiser Permanente Vaccinate RCT found cardiovascular-focused electronic nudges did not increase influenza vaccination rates versus usual messages.
- Trial context and trust in the messenger strongly affect nudge effectiveness across health systems.