Child Neurology Society's Brainstorm CNS Brainstorm Episode 6 "Pediatric Stroke" with guest Lori Jordan, MD, PhD
Mar 4, 2025
Lori Jordan, MD, PhD, is an Associate Professor of Pediatrics and Director of the Pediatric Stroke Program at Vanderbilt University, specializing in pediatric stroke. In this discussion, she highlights the unique aspects of pediatric strokes, emphasizing the need for greater medical awareness. Topics include risk factors by age, advancements in treatment options, and the importance of prompt management strategies, especially for conditions like sickle cell disease. Additionally, she underscores significant research developments, particularly linking strokes to viral infections and the ongoing challenges in pediatric stroke care.
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Pediatric Stroke Epidemiology
- Pediatric stroke is more common than people realize, affecting approximately 1 in 3,000 births (perinatal) and 3 in 100,000 children annually.
- Half of childhood strokes are hemorrhagic, unlike adult strokes, where ischemic strokes are more prevalent.
Managing Suspected Newborn Stroke
- If a newborn has a suspected stroke, examine the placenta for clots to determine the etiology.
- Routine hypercoagulability testing is not recommended for infants with perinatal stroke.
Perinatal Stroke Risk Factors and Presentation
- Perinatal strokes often lack identifiable risk factors, but male sex is associated with increased risk.
- Later-presenting perinatal strokes may manifest as early hand preference or seizures around 4-6 months.