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Mind-Body Solution

Karl Friston: How Does Death Shape Life?

Dec 17, 2023
Neuroscientist Karl Friston discusses the meaning of life and how death shapes our perception. He explores mortal computation and provides real-world examples. The podcast also covers topics such as adaptive resonance theory, synaptopathy, Bayesian brains, mental health, and diverse intelligence field. Friston also mentions influential figures like Andy Clark, Mark Solms, Gerald Edelman, and Anil Seth.
01:56:17

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Quick takeaways

  • Understanding and treating synaptopathies is important in healthcare as it directly impacts sensory processing, attentional gain, and sensory attenuation processes.
  • Collaboration and the integration of diverse perspectives from various disciplines are essential in advancing the field of neuroscience, psychology, and philosophy.

Deep dives

Synaptopathy and its Relevance to the Bayesian Brain and Healthcare

Synaptopathy refers to a pathology of synapses, the microscopic connections between brain cells that enable communication. It encompasses various conditions where synaptic connectivity is disturbed, leading to neurological or psychiatric diseases. Synaptic connections play a crucial role in the Bayesian brain and predictive processing, as they determine the connection weights in neuronal networks. Dysfunction or modulation of synapses can result in a breakdown of modulatory effects, affecting how prediction errors are reported and updating beliefs. Synaptopathies can disrupt precise modulation of synapses, leading to false inferences, such as hallucinations or neglect syndromes. Understanding and treating synaptopathies is important in healthcare, as it directly impacts sensory processing, attentional gain, and sensory attenuation processes.

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