

Depression and Family History: How Genetics and Trauma Shape Mental Health
What role does family history play in depression and other mental health conditions? In this episode of Giving Voice to Depression, guest Matt Zinman shares his lived experience of growing up in a family deeply impacted by bipolar disorder, depression, and suicide attempts. His story highlights how genetics and environment often intersect, shaping the way depression shows up across generations.
Matt also opens up about his own struggles with depression, suicidal ideation, and the difficult emotions that arise when loved ones attempt or die by suicide. Alongside Terry, Bridget, and Dr. Anita, this conversation explores the complicated mix of anger, grief, compassion, and hope that accompany living with depression in families where mental health struggles are part of the legacy.
Listeners will come away with a better understanding of why depression can feel "inherited," what research actually says about genetics and mental health, and the importance of building supportive networks and tools for resilience.
Primary Topics Covered:
- What research tells us about genetics and depression
- How family history increases risk for mental illness
- Growing up with a parent living with bipolar disorder and depression
- The long-term impact of parental suicide attempts
- Coping with a sibling’s death and opioid struggles
- The complexity of anger, grief, and compassion after suicide
- Medication struggles and suicidal ideation as a side effect
- The gaps in mental health care and why inpatient treatment can be necessary
- Building a personal “safety net” of supportive people
Timestamps:
00:00 – Introduction to the podcast and hosts
01:34 – The role of genetics in depression and mental health disorders
02:21 – Sisters’ reflections on family history of depression and bipolar disorder
03:11 – Guest introduction: Matt Zinman’s lived experience
04:07 – Growing up with a bipolar father and depressive mother
05:21 – Early exposure to suicide attempt as a child
06:13 – Anger, confusion, and disconnect after a parent’s attempt
07:10 – Matt’s first personal experiences of depression
08:00 – The loss of his brother and the opioid crisis impact
08:31 – Holding both anger and compassion for loved ones lost to suicide
11:05 – Medication struggles and suicidal ideation as a side effect
12:22 – The gaps in accessible, ongoing mental health care
13:33 – Why focusing on people who “lift us up” matters
14:42 – The complexity of emotions when loved ones struggle with suicide
16:16 – Bridget shares her own medication-induced depression experience
17:28 – Closing reflections and reminder to not believe everything your brain tells you
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